Saffron, a spice widely used in Middle Eastern cooking, may offer benefits for mental health, including easing symptoms of depression.
Dr. Daniel Amen, psychiatrist and founder of Amen Clinics in California, told Fox News Digital that he regularly recommends saffron for its mood-boosting properties.
“I love saffron so much,” he said. “I’m Lebanese, and Middle Eastern folks cook with a lot of saffron. And there’s actually folklore in Iran: If you’re too happy, you must have had saffron.”
Research supports Amen’s enthusiasm. Studies have shown that about 30 milligrams of saffron per day may be as effective as certain antidepressants in randomized trials. Beyond mood support, saffron has also been linked to improved memory and focus.
A 2025 study published in Reviews in Clinical Medicine found that saffron could also significantly reduce premenstrual syndrome (PMS) symptoms after 8–12 weeks of use.
Meanwhile, a review published by Cambridge University Press in May 2025 analyzed 192 trials with over 17,000 participants, highlighting saffron as one of the most effective nutraceuticals for easing depression.
Amen also recommends combining saffron with other supplements like zinc and curcumins (natural compounds in turmeric) alongside prescription antidepressants to potentially enhance results.
While cooking with saffron can add flavor and a small mood lift, therapeutic doses are usually achieved through supplements, available as capsules, tablets, or powdered extracts.
As always, it’s imperative to consult with your doctor before taking any saffron supplements.
Dining and Cooking